Liposomes in drug delivery

Cover of: Liposomes in drug delivery |

Published by Harwood Academic Publishers in Chur, Switzerland, Langhorne, Pa .

Written in English

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Subjects:

  • Liposomes.,
  • Drugs -- Vehicles.,
  • Drug Delivery Systems -- congresses.,
  • Liposomes -- pharmacology -- congresses.,
  • Liposomes -- therapeutic use -- congresses.

Edition Notes

Includes bibliographical references and index.

Book details

Statementedited by Gregory Gregoriadis and Alexander T. Florence, Harish M. Patel.
SeriesDrug targeting and delivery ;, v. 2
ContributionsGregoriadis, Gregory., Florence, A. T., Patel, Harish M., 1939-
Classifications
LC ClassificationsRS201.L55 L575 1993
The Physical Object
Paginationxv, 256 p. :
Number of Pages256
ID Numbers
Open LibraryOL1742622M
ISBN 10371865265X
LC Control Number92049658

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Liposomes in Drug Delivery (Drug Targeting and Delivery) 1st Edition by Alexander T. Florence (Author), Gregory Gregoriadis (Author), Harish M. Patel (Author) & See all formats and editions Hide other formats and editions. Price New from Used from Hardcover "Please retry" $ Cited by: Book Description.

This book is an outcome of the conference on the liposomes in drug delivery: 21 years held in University of London, in It covers themes such as novel carrier systems, newer and potential responsive or pulsatile systems, or systems such as liposomes which have a longer pedigree.

DOI link for Liposomes in Drug Delivery. Liposomes in Drug Delivery book. Liposomes in Drug Delivery. DOI link for Liposomes in Drug Delivery. Liposomes in Drug Delivery book. By AlexanderT. Florence.

Edition 1st Edition. First Published eBook Published 5 October Pub. location by:   Liposomes as drug delivery vehicles will find broader applications with the study of tailor‐designed lipids in conjunction with the therapeutic agents to be delivered. It is important that for certain types of drugs, the liposomes used should also be tailored to match the physical and chemical properties of the by: 8.

Buy Liposomes in Drug Delivery (Drug Targeting and Delivery Book 2): Read Kindle Store Reviews -   This book is an outcome of the conference on the liposomes in drug delivery: 21 years held in University of London, in It covers themes such as novel carrier systems, newer and potential responsive or pulsatile systems, or systems such as liposomes which have a longer pedigree.5/5(1).

Abstract. Liposomal drug delivery system has made evident breakthrough and innovation in the fields Liposomes in drug delivery book drug treatment. The objectives of this chapter are to briefly review the features, classification, major preparation materials and methods, and application of drug liposomes.

In book: Biological and Pharmaceutical Applications of Nanomaterials (pp) Chapter: Liposomes as a Drug Delivery System; Publisher: CRC Press.

Liposomes are a novel drug delivery system (NDDS), they are vesicular structures consisting of bilalyers which form spontaneously when phospholipids are dispersed in water.

They are microscopic vesicles in which an aqueous volume is entirely Liposomes in drug delivery book by a membrane composed of lipid bilayers. NDDS aims to deliver the drug at a rate directed by the needs of the body during the period of. Liposomes as a drug delivery system include benefits like improved pharmacokinetics and pharmacodynamics, decreased toxicity, enhanced therapeutic efficacy against pathogens and improved drug-target selectivity.

The disadvantages, on the other hand are: certain lipids, especially charged lipids, become toxic in increased doses, sterilization is. Research in the field of liposomes aims now at the development of various liposome-based multifunctional nanopreparations for therapy and diagnostics or for both simultaneously (theranostics).

This chapter briefly addresses the basic properties of liposomes as drug delivery systems and the development and current status of some liposomal by:   Figure 1.

Structural and design considerations for liposomal drug delivery. Liposomes can be surface functionalized to endow stealth through PEGylation and to promote receptor-mediated endocytosis by using targeting ligands such as antibodies, peptides, proteins, carbohydrates, and various other small by: Article highlights.

Innovative designs in liposomal architectures are contributing to the optimization of drug activity in vitro and, more promisingly, in vivo.

Sincepublished patents are describing new hopeful possibilities to engineer stable liposomes exhibiting excellent drug delivery capabilities. This short-review focuses on the use of liposomes in anti-cancer drug delivery. Cancer is a life-threatening disease contributing to ~ million deaths worldwide.

There are various causes of cancer, such as smoking, being overweight or obese, intake of processed meat, radiation, family history, stress, environmental factors, and by: Review Article LIPOSOMES: A NOVEL DRUG DELIVERY SYSTEM PRIYANKA R KULKARNI*, JAYDEEP D YADAV, KUMAR A VAIDYA Department of Pharmaceutical Sciences, N.D.M.V.P.

Samaj’s, College of Pharmacy,Gangapur Road, Nasik­Maharashtra, India. Email: [email protected] Liposomes have been widely used in pulmonary drug delivery for ­multiple applications including solubilization, sustained release, cellular and intracellular ­targeting, minimization of toxicity.

Liposomal drug delivery systems are very effective in the delivery of vaccines and genes due to their adjuvant property and targeting ability which elicit the immune response of the body through antibody formation and corrected gene inputs.

Along with this, the mechanism of vaccine and gene delivery is. The development of liposomes as a drug delivery system has fluctuated since its introduction in the late 's by A.D. Bangham. While academic research of liposomes as a model membrane system has always flourished, as the exponential growth of papers can testify, the application of these findings to medically useful products has gone through several crises.

This volume mainly describes the protocols for fabrication of liposomal drug delivery system, and consists of three parts, namely, the advances in liposome-based drug delivery system, the general protocols for fabrication of drug-loading liposomes, and the protocols for preparation of functionalized liposome-based drug delivery system.

Considering liposomal drug delivery system in the future, novel drugs can be converted into convectional liposomes with enhanced circulation.

Delivery of ribozymes and oligonucleotides is also assured in future. Encapsulated allergens and blood based artificial liposomes are the future applicant for development and are used in allergy treatment. Additionally, liposomes possess features of optimal drug delivery systems to get to the ocular surface and intraocular tissues, for instance, sustained and controlled drug delivery, ease to instill for the patient, good corneal-scleral penetration, and the fact that they reach appropriate concentrations of the drug in the target tissue, avoid Cited by: 1.

Liposomal drug-delivery systems were the first strategies for delivery of drugs through the transdermal route, since the nature of liposomes gives them the potential of exerting different functions after topical applications (Maghraby et al., ; Zellmer et al., ; Heinrich et al., ; Chen et al., ).

Book Description. Many specialists are not familiar with both drug delivery and the molecular biology of DNA vectors. Liposomes in Gene Delivery covers both-molecular biologists will gain a basic knowledge of lipids, liposomes, and other gene delivery vehicles; lipid and drug delivery scientists will better understand DNA, molecular biology, and DNA manipulation.

‎Liposomes are synthetic vesicles consisting of one or more phospholipid bilayers, able to accommodate water- and lipid-soluble molecules. They are used as a delivery system for drugs, genes and vaccines in therapeutics. This collection of reviews and laboratory protocols provides the read. Liposome Drug Delivery (Liposomes Drug Delivery) Market Liposomes are drugs that are used in enhancing drug absorption, achieve target drug delivery, increase half-life of drug, and reduce.

ISBN: X X OCLC Number: Description: xv, pages: illustrations ; 26 cm. Contents: Use of liposomes as carriers of lipophilic antitumor agents / R. Perez-Soler [and others] --Phase II trial of liposome-encapsulated doxorubicin in advenced measurable breast cancer / A.

Rahman, P.V. Woolley and J. Treat --Initial clinical. Introduction: Pharmacotherapy is limited by the inefficient drug targeting of non-healthy cells/ this pharmacological landscape, liposomes are contributing to the impulse given by Nanotechnology to optimize drug therapy.

Areas covered: The analysis of the state-of-the-art in liposomal formulations for drug delivery purposes have underlined that lately published patents (since We constructed the presented PCL8-U75 L-OHP liposomes to overcome the problems associated with liposomal chemotherapeutic drug delivery systems.

The PCL8-U75 successfully achieved optimal systemic circulation and tumor-accumulating properties even at repeated administrations while having potent in vitro and in vivo therapeutic efficacy. Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption.

Summarizing recent research in the field, Colloids in Drug Delivery assembles5/5(1). Examines the standard method of accomplishing controlled drug release through the incorporation of the drugs within polymeric biomaterials such as capsules and microcapsules as well as other vehicles such as liposomes Discusses various controlled drug delivery systems, including sustained release delivery systems and pulse or delayed release, e.

In addition to gene and drug delivery applications, liposomes can be used as carriers for the delivery of dyes to textiles, pesticides to plants, enzymes and nutritional supplements to foods, and cosmetics to the skin. Liposomes are also used as outer shells of some microbubble contrast agents used in contrast-enhanced ultrasound.

The future of liposomal drug delivery Biotechnol Appl Biochem. Oct;12(5) Author F C Szoka Jr 1 Affiliation 1 School of Pharmacy, University of California, San Francisco PMID: Abstract Liposomes are microvesicles composed of continuous bilayers of phospholipid surrounding an aqueous phase.

Abstract: Since the discovery of liposomes, the drug delivery technology has made a tremendous advancement in the field of medicine. Owing to their biocompatibility, efficacy, targeting ability and improved in vivo performance, liposomes has become popular as versatile drug carrier systems.

Liposomal Drug Delivery An Overview Sciencedirect Topics Liposomes In Drug Delivery Drug Targeting And Delivery this book is an outcome of the conference on the liposomes in drug delivery 21 years held in university of london in it covers themes such as novel carrier systems newer and potential responsive or.

PEGylation of liposomes not only is essential to achieve long systemic circulation of liposomes but also impedes drug release, depending on liposome composition and cell interactions (25).

To overc this, we constructed a liposomal L-OHP drug delivery system based on a cationic unsaturated lipid composition shielded with a nega.

Liposomal doxorubicin loaded PLGA-PEG-PLGA based thermogel for sustained local drug delivery for the treatment of breast cancer. Artificial Cells, Nanomedicine, and Biotechnology47 (1),   In recent years, liposomes have been employed with growing success as pharmaceutical carriers for antineoplastic drugs.

One specific strategy used to enhance in vivo liposome-mediated drug delivery is the improvement of intracytoplasmic delivery. In this context, pH-sensitive liposomes (pHSLip) have been designed to explore the endosomal acidification process, which may lead to a.

Liposomes, on the other hand—well established in the drug delivery field—boast a proven safety track record, plus, they’re quite easy to make, Wei Deng, Ph.D., lead research author, said in.

Liposomes are small spherical vesicles composed mainly of phospholipids and cholesterol. Over the years, a number of liposomal formulations have shown clinical promise, but the use of liposomes in oral drug delivery is limited.

This is partly due to the vulnerability of conventional liposomes to the detrimental effect of gastrointestinal destabilizing factors and also to the poor efficiency in.

Luye Pharma Liposome Drug Delivery (Liposomes Drug Delivery) Sales, Price, Revenue, Gross Margin and Market Share () Sigma-Tau Group Business Overview. According to this study, over the next five years the Liposomes Drug Delivery market will register a % CAGR in terms of revenue, the global market size will reach $ million byfrom $ million in Twenty years after the introduction of liposomes to drug delivery, the pharmaceutical industry witnessed a paradigm shift with USFDA approval of Doxil ™ (Alza Corporation) in the year (Weissig, ).

It was the first marketed injectable liposomal formulation that corroborated the prescience of Bangham and associated scientists.2 days ago  The Global Liposomes Drug Delivery Market Outlook toCapacity, Generation, Investment Trends, laws, and Company Profiles.

The business examination pros that give exhaustive information and comprehension of the Liposomes Drug Delivery market inside the globe. The report gives a top to bottom investigation of the global Liposomes Drug Delivery market with estimates up .

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